Hertraz-Trastuzumab - Price in India, Side effects, Advantage

What is Hertraz-trastuzumab?

Hertraz (trastuzumab) is a medication used in the treatment of certain types of cancer, specifically breast cancer that is HER2-positive. HER2 (human epidermal growth factor receptor 2) is a protein that is overexpressed in some breast cancer cells, leading to more aggressive tumor growth.

Trastuzumab is a monoclonal antibody that targets and binds to the HER2 protein, inhibiting its activity. By binding to HER2, trastuzumab can help slow down or stop the growth of HER2-positive breast cancer cells. It can be used in both early-stage and advanced-stage breast cancer.

Advantage Of Hertraz Trastuzumab -

Effective in HER2-positive breast cancer: Hertraz is highly effective in treating HER2-positive breast cancer, both in the early and advanced stages. It specifically targets the HER2 protein, which plays a critical role in the growth and spread of HER2-positive breast cancer cells.

Improved survival rates: Clinical trials have shown that Hertraz, when used in combination with chemotherapy, significantly improves survival rates in patients with HER2-positive breast cancer. It has been shown to reduce the risk of disease recurrence and increase overall survival.

Adjuvant therapy: Hertraz is commonly used as an adjuvant therapy, meaning it is given after surgery to reduce the risk of cancer recurrence. It helps to destroy any remaining cancer cells and prevent the cancer from coming back.

Neoadjuvant therapy: In some cases, Hertraz may be used as a neoadjuvant therapy, which means it is given before surgery. This approach can help shrink tumors, making them easier to remove surgically. Neoadjuvant Hertraz has been shown to increase the likelihood of achieving a complete pathological response, meaning no residual cancer is found in the breast tissue removed during surgery.

Well-tolerated: Hertraz is generally well-tolerated by patients. The most common side effects include fever, chills, nausea, fatigue, and muscle aches. Severe adverse reactions are rare but can include allergic reactions and heart problems. Regular monitoring of heart function is necessary during treatment.

Long-term benefits: Studies have demonstrated that the benefits of Hertraz treatment can extend beyond the treatment period. Patients who receive Hertraz as part of their breast cancer therapy have shown improved long-term survival rates compared to those who do not receive Hertraz.

Side Effects Of Hertraz Trastuzumab -

Cardiac toxicity: Hertraz can affect the heart and may lead to a decrease in the heart's ability to pump blood properly. This can result in symptoms such as shortness of breath, fatigue, rapid or irregular heartbeat, and swelling of the ankles or legs. It is important to monitor heart function regularly during treatment with Hertraz.

Infusion reactions: Some people may experience infusion-related reactions during or shortly after receiving Hertraz through intravenous infusion. Symptoms can include fever, chills, nausea, vomiting, headache, dizziness, and rash. These reactions are usually mild to moderate in severity but can occasionally be more severe.

Allergic reactions: In rare cases, Hertraz can cause serious allergic reactions. Signs of an allergic reaction may include hives, itching, difficulty breathing, chest tightness, and swelling of the face, lips, tongue, or throat. If these symptoms occur, immediate medical attention is necessary.

Flu-like symptoms: Some individuals may experience flu-like symptoms such as fever, body aches, and fatigue while receiving Hertraz. These symptoms are usually mild and subside with time.

Gastrointestinal disturbances: Hertraz may cause gastrointestinal side effects, including nausea, vomiting, diarrhea, and abdominal pain. These symptoms are generally manageable with supportive care and medication if needed.

Weakening of the immune system: Hertraz can lower the activity of the immune system, making individuals more susceptible to infections. It is important to watch for signs of infection, such as fever, sore throat, and persistent cough, and promptly report them to your healthcare provider.

Low blood cell counts: Hertraz can sometimes cause a decrease in the number of white blood cells, red blood cells, and platelets. This can lead to an increased risk of infections, anemia (low red blood cell count), and bleeding or bruising. Regular blood tests are usually conducted to monitor blood cell counts.

Conclusion 

Hertraz is typically administered intravenously (through a vein) and is often given in combination with other chemotherapy drugs or targeted therapies, depending on the specific treatment regimen prescribed by the oncologist.  As with any medication, Hertraz may have side effects, which can vary from person to person. Common side effects may include fatigue, nausea, vomiting, diarrhea, headache, fever, rash, and muscle pain. Some individuals may also experience more serious side effects, such as heart problems or infusion reactions