Heal it up with best pharmaceutical suppliers

 In a bitter paradox, antibiotics fuelled the growth of the twentieth century’s most profitable pharmaceutical companies, and are one of society’s most desperately needed classes of drug. Yet the market for them is broken. For almost two decades, the large corporations that once dominated antibiotic discovery have been fleeing the business, saying that the prices they can charge for these life-saving medicines are too low to support the cost of developing them. Most of  pharmaceutical suppliers  now working on antibiotics are small biotechnology firms.

Bringing a new antibiotic to market is a miraculous feat. Only about 14% of antibiotics and biologics in Phase 1 trials are likely to get approval, according to the World Health Organization. A team of economists1 estimated in 2016 that the cost of going from the first identification of an active drug molecule to approval by the Food and Drug Administration in the United States was $ 1.4 billion, and millions more were needed for marketing follow-up and post approval. 

And when, as is often the case, large companies bought smaller companies whose new drugs were preclinically promising, the purchase price covered the debts incurred by small companies.

As a side effect of the pandemic, many other antibiotics are in short supply. That’s a result of both interruptions in international trade — the active ingredients of most antibiotics come from China — and domestic influence. For instance, the unproven and now largely discredited combination of hydroxychloroquine and azithromycin, several manufacturers of azithromycin announced that panic buying had triggered shortages.

A surplus of antibiotics is not a good thing. There may be times when you have some left over from a prescription. If that happens, Spires says, you should throw the remainder away. This is because antibiotics are prescribed for specific conditions, at specific times. Taking a leftover medication for a future illness, even if the symptoms seem similar, is dangerous.